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Chinese Medicine：针灸治疗白癜风的分子机制新解析

13小时前 吾乃喵大人 MedSci原创 发表于上海

针灸白癜风
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该研究不仅在临床患者中验证了FFN的安全性和有效性，更在单苯酚诱导的白癜风小鼠模型中阐明了其通过调控免疫信号通路保护黑色素细胞的分子生物学基础，为针灸治疗白癜风奠定了坚实的科学依据。

亮点总结 首次系统揭示了丝状火针疗法通过下调Mfsd4a表达，抑制IL-6驱动的JAK/STAT3信号通路，从而保护黑色素细胞免受T细胞介导的凋亡。 在患者及单苯酚诱导的动物模型中，丝状火针显著促进病灶色素恢复，减少免疫炎症因子水平，验证其临床和实验疗效。 研究阐明了Mfsd4a在黑色素细胞存活和黑色素合成中的关键调控作用，推动了针对分子靶点的白癜风治疗策略探索。 白癜风是一种常见的自身免疫性皮肤色素脱失病，其核心机制涉及多种免疫细胞对白细胞施加攻击，导致黑色素细胞凋亡和功能障碍。2025年发表于《Chinese Medicine》上的最新研究——“Filiform fire needling therapy relieves T cells-mediated melanocyte apoptosis and dysfunction by inhibiting JAK/STAT3 pathway via Mfsd4a in vitiligo”，首次探究了丝状火针（FFN）治疗白癜风的分子机制。该研究不仅在临床患者中验证了FFN的安全性和有效性，更在单苯酚诱导的白癜风小鼠模型中阐明了其通

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    2小时前 八骏奔腾 来自山东省


    前往app查看评论内容

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    6小时前 135672_1610 来自山东省


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    11小时前 Dew· 来自新疆


    前往app查看评论内容

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    13小时前 ms4000001513304915 来自广东省


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    13小时前 梅斯管理员 来自上海

    #针灸# #白癜风#

    0

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J Cosmet Dermatol：针灸能否有效改善眉间纹？一项随机对照试验的循证研究

随着预期寿命的延长，面部年轻化的重要性日益凸显。由于现代高压生活方式导致频繁皱眉动作，眉间纹已成为面部上1/3区域最常见的皱纹。其形态可呈垂直、水平或斜向分布，具体取决于主导肌肉（降眉间肌、皱眉肌或二

浙江大学顾臻、张宇琪/上海交大樊春海院士/天津中医药陈波：针灸启发的微针疗法，登上Cell新刊！

本文介绍了一种新型的工程化微针贴片，用于增强针灸疗法治疗2型糖尿病和骨关节炎的效果。

十三鬼穴：中医针灸里的什么穴位组合

“十三鬼穴” 是中医针灸治疗精神类疾病的特殊穴位组合，源于唐代，有特定定位和作用。现代认为其疗效与调节神经系统有关，应用时需专业操作，结合其他疗法，且存在禁忌，建议中西医结合治疗精神疾病。

【中西合璧】基于多组学分析的针灸治疗遗忘性轻度认知障碍的微生物-肠-脑轴机制的发现：一项初步研究

此项由四川中医药大学梁繁荣团队开展的随机对照试验，旨在初步探讨针刺是否通过调节MGB轴增强aMCI患者的认知能力。

【中西合璧】针灸治疗肠易激综合征的疗效（ACTION）：一项多中心随机对照试验

研究者开展了一项针灸治疗IBS的试点研究，以探讨针灸对先前试验方法学缺陷的协议可行性。

IF 25.6震撼突破！北京中医药大学最新临床研究：中医针灸治疗腹泻型肠易激综合征效果显著

该研究为针灸治疗 IBS 提供了有力的科学依据，有望改写 IBS 的治疗格局。

【中西合璧】针灸疗法治疗癌痛的有效性：一项系统综述及荟萃分析

本研究的结果表明，针灸可能是缓解癌症相关疼痛的有效干预措施。尽管一些纳入研究存在低质量和样本量小的局限性，以及癌症类型和分期的差异，但针灸可能提供一种有效且安全的癌症疼痛治疗方法。

颠覆性研究！针灸镇痛机理被发现？电针刺激激活蓝斑去甲肾上腺素能神经元，为术后镇痛提供新策略！

该研究深入探讨了电针刺激（Electroacupuncture，EA）在术后镇痛中的作用机制，揭示了其通过调节蓝斑去甲肾上腺素能-脊髓投射来发挥镇痛效果的奥秘。

夜尿多？针灸疗法“破局”！IF 22.3，JAMA子刊：针刺疗法改善前列腺癌夜尿频繁，提升整体泌尿功能

该研究首次探讨了针灸在前列腺癌幸存者夜尿症治疗中的应用，并取得了令人瞩目的成果。